Predicting Nucleosome Positioning based on DNA Sequence

摘要：

The genomic DNA in eukaryotic nucleus is packaged into nucleosomes that are the basic repeating units of eukaryotic chromatin. Each nucleosome contains approximately 146 base-pair (bp) genomic DNA that is wrapped in 1.75 turns around a histone octamer. Two neighboring nucleosomes are joined by a stretch of around 20-80 bp free DNA termed linker DNA. Nucleosomes not only play a basic structural role, but also participate in regulation of diverse processes of life, including replication, transcription, DNA repair, and etc.

作者: Lu Cai Xiujuan Zhao Zhiyong Pei Jia Liu

作者单位: Institute of Bioengineering and Technology, Inner Mongolia University of Science and Technology, Bao Institute of Bioengineering and Technology, Inner Mongolia University of Science and Technology, Bao

会议类型: 国际会议

会议名称: 第四届全国生物信息学与系统生物学学术大会

会议地点: 杭州

会议语种:英文

页码: 158-160

在线出版日期: 2010-10-01（万方平台首次上网日期，不代表论文的发表时间）