Quantitative structure-activity relationships of anti-HIV fusion inhibitors using Topomer CoMFA

摘要：

Nowadays, the HIV epidemic has always put huge threatens on human lives and the steady development of our society. Hence it is of great need to endeavor into the investigation of fundamental biology of Human Immunodeficiency Virus-1 (HIV-1) along with anti-HIV drug design. The process of HIV intrude into the host cell became central issue in new drug design area. The process of infection come down to the interaction between the glycoprotein (include gp l20, gp41) and receptor and co-receptor protein (include CD4, CCR5, CXCR4). The study of these proteins provide new target in HIV drug and vaccine design. Gp41 was the

作者: Wang Yao Chen Ying Ying Tan JianJun Wang Cun Xin

作者单位: College of Life Science and Bioengineering, Beijing University of Technology,Beijing 100124 College of Life Science and Bioengineering,Beijing University of Technology, Beijing 100124

会议类型: 国际会议

会议名称: 第四届全国生物信息学与系统生物学学术大会

会议地点: 杭州

会议语种:英文

页码: 179-180

在线出版日期: 2010-10-01（万方平台首次上网日期，不代表论文的发表时间）