The Genome-wide survey of MicroRNA and Transcription Factor-NF-κB regulatory network from Bioinformatics
MicroRNAs (miRNAs) are post-transcriptional regulators which bind to complementary sequences in the three prime untranslated regions(3 UTRs) of target messenger RNA transcripts (mRNAs). Nuclear factor kB (NF-kB) is a nuclear transcription factor that regulates expression of a large number of genes, acting at the transcriptional level. MicroRNAs and NF-kB are closely related to and may regulate each other in theory. MicroRNAs which transcript from the genome would regulated by the NF-kB, which is a typical and widely functioned family of Transcription Factors (TFs);and on the other hand, NF-kB might also be regulated by the microRNAs when its protein coding gene transcripts from the DNA to mRNA, which is the
Yunfei Bai Dai Lin
Southeast University, school of Biological Science and Medical Engineering, State Key Laboratory of Southeast University, school of Biological Science and Medical Engineering,State Key Laboratory of B
国际会议
杭州
英文
220-221
2010-10-01（万方平台首次上网日期，不代表论文的发表时间）