Biocompatibility and Conductpmetric Property of Sol-Gel Derived ZnO/PVP Nanocomposite Biosensor Film
Nanocrystalline ZnO and ZnO/PVP nanocomposite films have been prepared by the sol-gel dip-coating technique from zinc acetate precursor on silicon wafer and Pyrex glass substrates. The films were characterized using atomic force microscopy for morphology, and X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy for chemical analysis. Thermally untreated and annealed films were studied in order to analyze the influence of temperature on the formation and properties of the films. The films have a uniform void-free surface and the grain size increases with the annealing temperature. The cell viability Zssays indicate that the growth rate of BPH cells incubated in the presence of ZnO was significantly reduced (35％ of the control) compared to that of untreated controls, indicating antibacterial activity of ZnO as a result of the generation of hydrogen peroxide. The sensor characteristic of ZnO/PVP nanocomposite was also demonstrated by measuring the change in conductivity upon exposure to superoxide anion radical.
zinc oxide film biosensor nanocomposite film sol-gel
Olusegun J. Ilegbusi Hongwei Song Ratna Chakrabarti
Department of Mechanical, Materials and Aerospace Engineering, University of Central Florida, Orland Department of Molecular Biology and Microbiology, University of Central Florida, Orlando, FL 32816-2
国际会议
The 3rd International Conference of Bionic Engineering(第三届国际仿生工程会议ICBE10)
珠海
英文
30-35
2010-09-14（万方平台首次上网日期，不代表论文的发表时间）