Construction of Chinese Human Brain MRI Probabilistic Atlas Using HAMMER Elastic Reglstration Algorithm
Neural anatomical atlases serve as a reference coordinate system in neuroscience and clinical studies. Up to date, the most commonly used human brain templates are the Talairach brain coordinate system. The standard MNI (Montreal Neuroscience Institute) brain templates generated in early 1990s were based on a series of MRI scans from people of the western society. However, fundamental genetic and environmental disparities exist between the oriental and western human subjects, resulting in the overall and local brain shape and volume disparities. Such difference may cause mis-localization of activated brain regions during functional MRI experiments. It may also cause positional mismatches in the image-guided stereotactic neurosurgery. Therefore, it is of great significance to develop Chinese probabilistic brain atlases as the basis of Chinese human brain research projects. Here we present a preliminary study to construct MRI-based Chinese human brain templates using the automatic deformable HAMMER ( Hierarchical Attribute Matching Mechanism for Elastic Registration) registration algorithm. HAMMER algorithm is a robust registration algorithm which yields sharp average brain templates with high fidelity.
Rong Xue Xing Wang Zhentao Zuo Nan Chen Jing Luo Yan Zhuo Dinggang Shen Kuncheng Li
State Key Lab. of Brain and Cognitive Sclence, Institute of Biophysics,Chinese Academy of Sciences, Dept. of Radiology, Xuan Wu Hospital, Capital Medmcal Univ., Beijing, China Dept. of Radiology & BRIC, School of Medicmne, University of North Carolina, Chapel Hill, NC, USA
国际会议
The 7th International Conference on Cognitive Science(第七届国际认知科学大会 ICCS 2010)
北京
英文
107-108
2010-08-01（万方平台首次上网日期，不代表论文的发表时间）