Real-time observation of integrin bending/unbending conformational changes on living cells

摘要：

Integrins are a large family of adhesion molecules broadly expressed on the surface of a wide variety of cells as αβ heterodimers. Binding of integrins to ligands provides not only mechanical anchorage for the cell to another cell or extracellular matrix, but also biological signals bidirectionally across the cell membrane, making integrins prime candidates for mechanosensing molecules.

作者: Fan Yuan Nelita T. Elliott

作者单位: Coulter Department of Biomedical Engineering Georgia Institute of Technology, Atlanta, GA 30332-0363, USA

会议类型: 国际会议

会议名称: 第四届中美生物医学工程暨海内外生物力学学术研讨会

会议地点: 重庆

会议语种:英文

页码: 1-3

在线出版日期: 2010-07-26（万方平台首次上网日期，不代表论文的发表时间）