p38 MAP kinase is necessary for melanoma-mediated regulation of VE-cadherin disassembly

摘要：

Vascular endothelial (VE)-cadherin is localized to the endothelial borders and the adherens junctions, which are regulated by changes in mitogen activated protein kinases (MAPK), GTPases, and intracellular calcium. We previously showed that melanoma cells induce VE-cadherin disassembly through contact with human umbilical vein endothelial cell (HUVECs) in co-culture.

作者: Payal Khanna Avery August Cheng Dong

作者单位: Department of Bioengineering and Penn State University, University Park, PA 16802, U.S.A. Department of Veterinary & Biomedical Sciences, Penn State University, University Park, PA 16802, U. Department of Bioengineering and Penn State University, University Park, PA 16802, U.S.A.

会议类型: 国际会议

会议名称: 第四届中美生物医学工程暨海内外生物力学学术研讨会

会议地点: 重庆

会议语种:英文

页码: 16-18

在线出版日期: 2010-07-26（万方平台首次上网日期，不代表论文的发表时间）