Preparation of Surface Etched Ultra-fine Fibers via Electrospun Unsaturated Polyester Macromonomers/poly (3-hydroxybutyrate-co-3-hydroxyvalerate)

摘要：

It is expected that etched ultra-fine fibers can be prepared via electrospinning of two immiscible polymers blend and subsequently removing one of the polymers using selective solvent. Such fibers may have potential applications for sustained drug release. In this study, a new preparing method for etched ultra-fine fibers via cross-linking and solvent washing was developed. A blend fiber was composed by unsaturated polyester macromonomers /poly (3hydroxybutyrateco-3-hydroxyvalerate) (UPM/PHBV). When the PHBV content increased to a certain level, the fibers showed special etched surfaces because much more soluble PHBV was washed by solvent. The adsorption and releasing effect increased with increasing PHBV content, which could be useful in sustained drug release or nanofiltration.

关键词： unsaturated polyester macromonomers (UPM) poly(3- hydroxybutyrate- co-3- hydroxyvalerate) (PHBV) electrospinning Solvent washing sustained drug release

作者: LIU Shui-ping WEI Fa-yun CHEN Yan-mo

作者单位: State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University, Shanghai, 201620, China College of material science and engineering, Donghua University, Shanghai, 201620, China

会议类型: 国际会议

会议名称: 2010 International Forum on Biomedical Textile Materials(2010国际纺织生物医用论坛)

会议地点: 上海

会议语种:英文

页码: 211-214

在线出版日期: 2010-05-28（万方平台首次上网日期，不代表论文的发表时间）