Preparation of Quick-dissolving Ferulic Acid-loaded PVP Nanofiber Membrane through Electrospinning

摘要：

Ferulic acid (FA)-loaded polyvinylpyrrolidone (PVP K30) nanofiber membrane was prepared using electrospinning. Electrospinning conditions were confirmed by polarizing microscope. Morphology and structure of the nanofiber membrane was confirmed by scanning electron microscopy. Distribution status of Ferulic acid was observed by X-ray diffraction. The interaction between FA and PVP was analyzed by FT-IR. Results indicated that well-distributed and smooth fiber can be spun with a FA-to-PVP ratio of 1,8 (w/w). FA had good compatibility with PVP, and which was well distributed in the ultrafine fibers as an amorphous physical form.

关键词： quick-dissolving drug delivery system electrospinning nanofiber membrane ferulic acid polyvinylpyrrolidone

作者: YU Yang YU Deng-guang BRANFORD-WHITE Christopher QUAN Jing ZHU Li-min

作者单位: College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, 201620, Institute for Health Research and Policy, London Metropolitan University, London, UK College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, 201620,

会议类型: 国际会议

会议名称: 2010 International Forum on Biomedical Textile Materials(2010国际纺织生物医用论坛)

会议地点: 上海

会议语种:英文

页码: 332-336

在线出版日期: 2010-05-28（万方平台首次上网日期，不代表论文的发表时间）