Electrospun Hyaluronic Acid/Gelatin Nanofibrous Mats for Wound Dressing

摘要：

In this study, we successfully fabricated the nanofibrous mats of gelatin (GE) and hyaluronic acid (HA) using 2,2,2Trifluoroethanol (TFE)/-water (the volume ratio is 1 ∶ 1) as a solvent via electrospinning. The morphology of the electrospun nanofibrous mats was investigated by SEM. The average nanofibrous diameter increased with increasing blend ratio of HA to GE. Cell viability studies with fibroblast cells indicated that GE/HE blended nanofibrous mats promote cell growth, especially when the weight ratio of GE to HA was 6 ∶ 4. Our results suggest electrospun GE-HA nanofibrous scaffolds be potential candidates for wound dressing.

关键词： electrospinning nanofibers mats hyaluronic acid gelatin wound dressing

作者: YIN An-lin GAO Cai-jiu ZHANG Kui-hua WANG Hong-sheng HE Chuang-long MO Xiu-mei

作者单位: Biomaterials and Tissue Engineering Lab, College of Chemistry and Chemical Engineering and Biologica Biomaterials and Tissue Engineering Lab, College of Chemistry and Chemical Engineering and Biologica Biomaterials and Tissue Engineering Lab, College of Chemistry and Chemical Engineering and Biologica

会议类型: 国际会议

会议名称: 2010 International Forum on Biomedical Textile Materials(2010国际纺织生物医用论坛)

会议地点: 上海

会议语种:英文

页码: 436-440

在线出版日期: 2010-05-28（万方平台首次上网日期，不代表论文的发表时间）