Enhanced bioactivity of sandblasted and acid-etched titanium surfaces

Two new modified sandblasted and acid etched (SLA) surface methods had been used on commercially pure Ti (Cp-Ti) surface. Scanning electron microscopy investigation showed that modified SLA surfaces had micro- and nano-structure surface topography. Contact angle test showed that surface hydrophilicity was significantly increased after modified SLA surface modification. Human osteoblast-like MG63 cell attachment test showed that modified SLA surfaces would attach more cells than simple SLA surface. The alkaline phosphatase (ALP) activity assay indicated that ALP activity was enhanced on two modified SLA surfaces relative to SLA and mechanically polished Cp-Ti surface at early stage. Thus, subsequent chemical modification of SLA surface seems to be a promising method to generate better bioactive surface properties.
Titanium surface modification Sandblasted and acid etched Alkali and heat treatment alkaline phosphatase activity
Enwei Zhang Yanbo Wang Fei Gao Shicheng Wei Yufeng Zheng
State Key Laboratory for Turbulence and Complex System and Department of Advanced Materials and Nano Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studi
国际会议
青岛
英文
393-396
2009-10-09(万方平台首次上网日期,不代表论文的发表时间)