Wound Healing Based on PU/Hydrogel Nanocompounds Containing FGF-2 and Releated Dressings by Radiation Method
PU/hydrogel compounds prepared byγ-ray radiation technique were investigated in this study. We used nanosized clay solution or powder, Polyurethane (PU), thermosensitive N-isopropyl acrylamide (NIPAAm) and acrylic acid (AAc) as starting materials to prepare PU/hydrogel nanocomposite products. The dipping and weighing tests, Material Testing Machine (LLOYD) were utilized to analyze the physical and mechanical properties differentially. In addition, the drug release and wound closure experiments were also finished by Enzyme-link immunosorbent assay (ELISA) reader and five groups of treatment dressings. From the final results, We obtained that the PU/hydrogel composite incorporating FGF-2 as a wound dressing was able to effectively interact with the wound in a suitable moist healing environment. These composites make them more compatible with skin.
γ-ray radiation hydrogel composites Fibroblast growth factor-2 (FGF-2)
Te-Hsing Wu Hong Ru Lin Lie-Hang Shen Jia-Hau Li
Institute of Nuclear Energy Research, Taiwan Department of Chemical and Material Engineering, Southern Taiwan University of Technology, Taiwan
国际会议
青岛
英文
437-440
2009-10-09（万方平台首次上网日期，不代表论文的发表时间）