Based on the geometric center of Z curve of gene sequences comparison analyses
DNA gene sequences are the vectors of biologic genetic information. Z curves of gene sequences can convert character sequences into visual spatial curve, and it can improve the efficiency and accuracy of judging genetic sequences. This paper uses the geometrical center distance matrix of Z curve to analyze and compare gene sequences, and analyzes the effects of primary geometric center and secondary geometric center. It also base on the primary geometric center and secondary geometric center experimentizes on samples of 11 different common first kind speciesβ-globulin gene sequences to get their distance matrix, then constructing their evolutionary trees based on these distance matrix and NJ algorithm. Finally we use the method to build evolutionary trees for 39 common species, the accuracy reached 90％.
Bioinformatics Z curve Sequence Aliment NJ algorithm Evolutionary tree
Xu Yongan Wu Jie Shen Lingling Chen Ling
School of Information Engineering, Yangzhou University, Yangzhou 225009, China
国际会议
重庆
英文
1308-1312
2009-12-25（万方平台首次上网日期，不代表论文的发表时间）