Alterations of the ECM in Ovarian Carcinogenesis Studied by Second Harmonic Generation Imaging Microscopy

摘要：

We have used Second Harmonic Generation (SHG) imaging microscopy to quantify alterations in the fibrillar collagen assembly in ex vivo human malignant and normal ovarian tissues. We integrate 3D imaging measurements, bulk optical parameter measurements, and Monte Carlo simulations to isolate the structural factors that are different in these tissues.

关键词： (180.6900) Three-dimensional microscopy (190.4180) Multiphoton processes (190.2620) Harmonic generation and mixing (290.7050) Turbid media (290.4210) Multiple scattering

作者: Oleg Nadiarnykh Ronald B. LaComb Molly A. Brewer Paul J. Campagnola

作者单位: University of Connecticut Health Center, Center for Cell Analysis and Modeling, Department of Cell Biology, Farmington, CT 06030, USA

会议类型: 国际会议

会议名称: ACP2009亚太光纤通信与光电国际会议

会议地点: 上海

会议语种:英文

页码: 1-2

在线出版日期: 2009-11-01（万方平台首次上网日期，不代表论文的发表时间）