Force Spectroscopy of Single Receptor-Ligand Bond Using an Optical Trap

摘要：

Here we developed an thermal fluctuation assay using optical trap technique, which enables to visualize consecutive binding–unbinding transition and to unravel the bond dissociation at low spring cosntant and low loading rate. This novel method provided further understandings in monitoring biophysics of receptor–ligand interactions.

关键词： (000.0000) General (000.0000)

作者: Yan Zhang Ganyun Sun Ning Li Bo Huo Shouqin Lü Mian Long

作者单位: National Microgravity Laboratory and Center for Biomechanics and Bioengineering, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China

会议类型: 国际会议

会议名称: ACP2009亚太光纤通信与光电国际会议

会议地点: 上海

会议语种:英文

页码: 1-2

在线出版日期: 2009-11-01（万方平台首次上网日期，不代表论文的发表时间）