Dynamic Optical Coherence Elastography and Applications

摘要：

A novel, dynamic, non-invasive, high-speed dynamic optical coherence elastography (OCE) system has been developed for quantitatively mapping tissue biomechanical properties utilizing spectral-domain optical coherence tomography (OCT) and a mechanical wave driver. This dynamic OCE technique is based on solving wave equations without speckle tracking algorithms. Using phase-resolved imaging, we demonstrate OCE can map dynamic elastic moduli of normal and neoplastic ex vivo human breast tissue. This dynamic OCE technique is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young’s moduli are measured on human skin from different sites, orientations, and frequencies.

关键词： (110.4500) Optical coherence tomography (120.7280) Vibration analysis (120.5050) Phase

作者: Xing Liang Stephen A. Boppart

作者单位: Beckman Institute for Advanced Science and Technology, Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign

会议类型: 国际会议

会议名称: ACP2009亚太光纤通信与光电国际会议

会议地点: 上海

会议语种:英文

页码: 1-2

在线出版日期: 2009-11-01（万方平台首次上网日期，不代表论文的发表时间）