PROMOTIVE EXCRETION OF POLYCHLORINATED DIBENZOFURANS AND POLYCHLORINATED DIBENZO-p-DIOXINS BY FBRA IN PATIENTS WITH YUSHO
In this study, we examined the effects of fermented brown rice with Aspergillus oryzae (FBRA) on the promotive excretion of PCDFs and PCDDs in two groups of patients with Yusho, that is, groups A and B. Just before starting this study, contamination levels of PCDFs and PCDDs were about 2 times higher in group A than in group B. Group A took FBRA after each meal and tree times a day for the first one year only and group B took FBRA only for the second one year. The concentrations of PCDFs and PCDDs in the blood of groups A and B were also measured at the end of the first and second year. We computed the average amounts in the net reduction of PCDFs and PCDFs/DDs from the body of the patients. As a result, in group A, 85.0 and 99.6 ng-TEQ/patient, respectively, were excreted from the body of the patients. In group B, only 38.1 and 40.0 ng-TEQ/patient were excreted. Accordingly, promotive excretion of PCDFs and PCDDs from the patients with Yusho by FBRA seemed more effective in group A than in group B, namely, in the group with higher contamination.
Nagayama J Hirakawa H Kajiwara J Todaka T Shibata S Tsuji H Iwasaki T
Laboratory of Environmental Molecular Epidemiology,Graduate School of Medical Sciences,Kyushu Univer Department of Environmental Sciences,Fukuoka Institute of Health and Environmental Sciences,Fukuoka Department of Dermatology,Graduate School of Medical Sciences,Kyushu University,Fukuoka 812-8582,Jap Division of Internal Medicine,Kitakyushu-Tsuyazaki Hospital,Fukuoka 811-3307,Japan Genmaikouso Corp.,Sapporo 001-0012,Japan
国际会议
北京
英文
1-6
2009-08-24（万方平台首次上网日期，不代表论文的发表时间）