SIMULTANEOUS EXTRACTION AND ANALYSIS OF MELAMINE AND CYANURIC ACID FROM BABY FORMULA WITH USING SOLID PHASE EXTRACTION (SPE)
In this research we present a new strategy for analysis of melamine and cyanuric acid that utilizes solid phase extraction (SPE) to selectivity retain both melamine and cyanuric acid (CYA) using a single SPE sorbent. The SPE procedure allows melamine and cyanuric acid to either be eluted together for simultaneous detection or eluted in separate fractions allowing for independent analysis of each compound. The method presented had a limit of detection for melamine of 2 μg/kg with a limit of quantitation below 20 μg/kg. Detection limits for cyanuric acid (CYA) were slightly worse than melamine due to acidic nature of the compound and the lower response by the LC/MS/MS in negative ion mode, but detection limits were still far below required levels (LOD 4 μg/kg, LOQ 20 μg/kg). The extracts were suitable for either LC/MS/MS or GC/MS depending on the capabilities of the lab.
Countryman Sky Huq Shahana Mathews Terrel Kelly Kory
Phenomenex 411 Madrid Ave Torrance CA,90501
国际会议
北京
英文
1-5
2009-08-24（万方平台首次上网日期，不代表论文的发表时间）