MONO- TO OCTA- CHLORINATED DIBENZO-p-DIOXINS AND FURANS IN HUMAN SERUM: INDICATOR CONGENERS AND TEQS
The mono- to tri-chlorinated compounds have been less studied, however the less chlorinated PCDD/Fs may give valuable information for environmental and biological samples. Similarly, the isomer profiles can provide to estimate the origin of dioxin and related compounds. The mean human serum concentrations of ΣCl1-8DD/F and 17-toxic congeners were 1890 and 398 pg/g lipid (11.9 I-TEQ pg/g lipid), respectively. The profile for PCDDs was dominated by most chlorinated congeners: OCDD (> 58％), while decreasing concentrations with increasing degree of chlorination were seen for PCDFs; MCDF( > 83％), DiCDF ( > 6 ％). ΣCl1-3DD/Fs accounted for 77％ of the serum concentrations of ΣCl1-8DD/F. These results suggest that we are exposed to a large amount of ΣCl1- 3DD/Fs. Moreover, MCDF contributed more than 60％ of ΣCl1-8DD/Fs and highly correlated with ΣCl1-8DD/Fs. Above all, 2-MCDF could be a predictive indicator for ΣCl1-8DD/Fs (r=0.94). In regard to TEQ concentrations, 2,3,4,7,8-PeCDF and 1,2,3,7,8-PeCDD were predominant congeners and contributed more than 65 ％ of TEQ concentrations.
Park H Chang Y-S
School of Environmental Science & Engineering,Pohang University of Science and Technology (POSTECH),San 31,Hyojadong,Namgu,Pohang,Kyungbuk,790-784,Korea
国际会议
北京
英文
1-4
2009-08-24（万方平台首次上网日期，不代表论文的发表时间）