A TEMPORAL TREND STUDY OF HUMAN EXPOSURE TO FLUORINATED SKI WAX
Only a limited number of studies on human accumulation and elimination of perfluorinated compounds (PFCs) are available. In a previous study we observed elevated levels of PFOA in an individual who reported frequent use of fluorinated ski wax. The objective of the study was to assess the temporal accumulation and elimination of PFCs in blood. We aimed to compare the levels in ski wax technicians exposed to fluorinated ski waxes to those of the general population. Individual levels of 11 PFCs were measured in monthly blood samples collected before, during and after the ski season from eight technicians exposed to fluorinated ski wax. The perfluorocarboxylates PFOA (4.80-534 ng/mL), PFNA (0.76-163 ng/mL), PFDA (0.87-23.7 ng/mL) and PFUnDA (0.11-2.84 ng/mL) were present in all samples. PFHxA was found in blood collected during the ski season but not in the unexposed period. Blood levels of carboxylates were inversely correlated to the chain length, C8>C9>C10>C11. The perfluorosulfonate PFOS (0.28-26.7 ng/mL) was found at background levels in all samples and individual concentrations were unaffected by the ski wax exposure. Notably PFOA, PFNA, PFDA and PFHpA have high bioaccumulation potential and upon continued exposure reach levels far above current background levels for the general population.
Nilsson Helena K(a)rrman Anna Westberg H(a)kan Rotander Anna van Bavel Bert Lindstr(o)m Gunilla
Man-Technology-Environment (MTM) Research Centre,(O)rebro University,SE-701 82 (O)rebro,Sweden Man-Technology-Environment (MTM) Research Centre,(O)rebro University,SE-701 82 (O)rebro,Sweden Depar
国际会议
北京
英文
1-6
2009-08-24（万方平台首次上网日期，不代表论文的发表时间）