CHEMICAL MIXTURES: VALIDATION OF WEIGHT-OF-EVIDENCE PREDICTIONS FOR INTERACTIONS
Binary interactions of chemicals can be evaluated based on the toxicological and mechanistic data. Weight-of-evidence (WOE) predictions can be made regarding the direction (i.e., synergism, antagonism) of the interaction. The paper presents examples of validations of such predictions based on in vitro, in vivo, and epidemiological data.
Pohl Hana R.
Agency for Toxic Substances and Disease Registry (ATSDR),U.S. Department of Health and Human Services,Atlanta,Georgia 30333
国际会议
北京
英文
1-4
2009-08-24(万方平台首次上网日期,不代表论文的发表时间)