Mutagenicity of the Mixture of Polycyclic Aromatic Hydrocarbons (PAHs)
INTRODUCTION Polycyclic aromatic hydrocarbons (PAHs) and nitrated polycyclic aromatic hydrocarbons (NO2-)PAHs distributed widely in air, water and soil environments. It is well known that these compounds have been used in the production of many kinds of fuel, dye, pesticides, drugs and perfumes, etc. Thousands of chemical compounds were identified in diesel exhaust (Xu et al. 1981; Howard et al.1983; Paschke et al.1992). Many kinds of PAHs and (NO2-)PAHs were detected in airborne particulates in various regions (Gibson 1982; Greenberg et al.1985). Most of (NO2-)PAHs are mutagenic and carcinogenic (Tokiwa et al. 1981). For example, up to date, it is found that 1,6-dinitropyrene (1,6-DNP) is one of the strongest direct-acting mutagens (Matsushita et al. 1986), and even it is carcinogenic in experimental animals (Maeda et al. 1986).
Xijuan Xia Shan Fu Naikai Zhu xiaobai Xu
Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences,Beijing,100085,CHINA
国际会议
北京
英文
1-7
2009-08-24(万方平台首次上网日期,不代表论文的发表时间)