DETERMINATION OF OCTANOL-WATER PARTITION COEFFICIENT FOR DDTS USING RP-HPLC
A reversed phase-high performance liquid chromatographic (RP-HPLC) method is applied for determining octanol-water partition coefficient (Kow) of DDTs. For this purpose, a semi-experimental equation is established by plotting a set of shake-flask Kow values against the corresponding corrected retention times (CRT) of 10 benzene homologues, which are chosen as model compounds in this study. The physicochemical data Kow for 3 DDTs (p,p-DDD, o,p-DDT, and p,p-DDE) and Dicofol were calculated by using this equation. In addition, the measured log Kow values for verification compounds (p,p-DDT and HCB) determined by RP-HPLC method and software-computed method were compared against shake-flask data respectively, and the RP-HPLC values were found to give better consistency with shake-flask results.
Han S Y Qiao J Q Zhang Y Y Yang L L Lian H Z Chen H Y
Key Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China),School of C Nanjing Environmental Monitoring Center,175 Huju Road,Nanjing 210013,China
国际会议
北京
英文
1-6
2009-08-24（万方平台首次上网日期，不代表论文的发表时间）