Fabrication of Novel Cellulose / Chitosan Artificial Skin Composite
Skin wounds, burns and scars represent a major burden upon world healthcare costs. The successful creation in vitro of skin substitutes has been the focus of a concentrated research activity for the last 30 or more years, culminating in some success for its translation into the clinical setting. In this paper, a novel artificial skin of bacterial cellulose has been biosynthesized by Acetobacter xylinum and modified by chitosan. BC is thought as an optimal substrate material of artificial skin. It is thought to be an interesting material for using as a substratum of artificial skin because it could provide moist environment to a wound resulting in a better wound healing. But BC has no antimicrobial activity to reduce the probability of wound infection. To achieve antimicrobial activity of BC, it was modified by chitosan due to its antibiotic activity. The structure and components were characterized by FTIR and ESEM. The results indicated the nano-composites of BC and chitosan are promising and potential for wound dressings.
Bacterial Cellulose Chitosan Skin
Lina FU Wei WANG Longjiang YU Shengmin ZHANG Guang YANG
College of Life Science and Technology, HUST, Wuhan, China College of Life Science and Technology, HUST, Wuhan, China Advanced Biomaterials and Tissue Engineer
国际会议
重庆
英文
1034-1038
2008-06-09（万方平台首次上网日期，不代表论文的发表时间）