Human Platelet Extracts Stimulate the Terminative Differentiation of Growth-plate Chondrocytes in Rabbit
Objective: To observe the effect of human platelet extracts on proliferation and differentiation of rabbit growth-plate chondrocytes in monolayer and fabrication of tissue engineering cartilage in vitro. Method: To determine the effects of platelet extracts at different concentrations on proliferation and differentiation of rabbit growth-plate chondrocytes using 3H-TdR、PNP and HE staining. Results: Platelet extracts had very strong stimulative effects on proliferation and differentiation of chondrocytes, especially the hypertropization (termination) of chondrocytes.
Human Blood Platelet Extracts Growth-plate Chondrocytes Proliferation Differentiation
Li YU MingQiao TANG WeiQun YAN
Department of Biochemistry, medical collage of Jinan University , Guangzhou 510632, China Department of Civil Engineering, Jinan University, Guangzhou 510632, China Institute of Preclinical of Sciences, Jilin University, Changchun 130021, China
国际会议
重庆
英文
1070-1075
2008-06-09(万方平台首次上网日期,不代表论文的发表时间)