Surface Characteristics and Hemocompatibility of Modified NiTi Alloy Intravascular Stents
TiO2, ZrO2 and titanium oxide in deficiency oxygen environment were used to modify the surface of biomedical NiTi stents. The coatings were prepared by vacuum deposition. The surface microstructures and characteristics, blood compatibility of the modified stents in simulated body fluids were assessed using scanning electron microscopy (SEM), hemolysis test, coagulation test and blood platelet adhesion test. The hemocompatiblity of the modified stents were all improved by layer coating. Enhancement of blood compatibility was believed to stem from the improved surface water affinity and hemolysis resistance of the layer, and titanium oxide in deficiency oxygen environment displayed better. This study indicated that layer coating was a promising effective modification method for improving the surface properties of biomedical NiTi alloy intravascular stents. As a coating materials，titanium oxide in deficiency oxygen environment was better than TiO2 and ZrO2.
Surface Modification TiO2 ZrO2 Hemocompatibility
Yaru NI Hairong HUANG Chunhua LU Junkai XUE Zongzi XU
College of materials science and technology, nanjing university of technology,Xinmofan Road 5, Nanji Department of Cardiothoracic Surgery, Jinling Hospital, Zhongshandong Road 305, Nanjing, 210029, Chi
国际会议
重庆
英文
1082-1089
2008-06-09（万方平台首次上网日期，不代表论文的发表时间）