Effect of the Surface Energy on the Biomineralization Behavior and Cell Compatibility of Carbonated Hydroxyapatite
Carbonated hydroxyapatite (CHA) and hydroxyapatite (HA) were prepared by the wet chemical method. The contact angle was measured to calculate the surface energy. The biomineralization process in SBF solution of HA and CHA were investigated in vitro. The cell attachment and proliferation behavior of CHA and HA were compared by the cell culture experiments. The results show that the polar component of surface energy of B-type CHA is higher than that of HA. Osteoblastic cells attach and proliferate very well on the surface, which indicates the excellent cell compatibility. The CHA have high bioactivity owing to rapid formation of hydroxyl-carbonate-apatite (HCA) mineralized layer on the biomaterials surface in SBF.
Carbonated Hydroxyapatite Surface Energy Biomineralization Cell Compatibility
Qingxia ZHU Jianqing WU Qing FENG Heping WANG
Jingdezhen Ceramic Institute, Jingdezhen 333001, China School of Materials Science and Engineering, South China University of Technology, Guangzhou 510640,
国际会议
重庆
英文
1203-1207
2008-06-09（万方平台首次上网日期，不代表论文的发表时间）