Protein Adsorption Behaviors on PLLA Surface Studied by Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D)
The adsorption of two different proteins (bovine serum albumin (BSA) and collagen-I) onto poly (L-lactic acid) (PLLA) surface was investigated using quartz crystal microbalance with dissipation monitoring (QCM-D) and atomic force microscopy (AFM). Its found that protein characteristics would greatly affect the adsorption kinetics, structure and viscoelastic properties of adsorbed protein layers. Compared with BSA, collagen-I trended to form a loose, dissipative layer with a slower adsorption rate and larger adsorption reversibility, which is consistent with AFM observation. The results provided some valuable information for controlling the structure and properties of adsorbed proteins to develop an alternative surface-modification approach for biomaterials.
Biomaterials Protein Adsorption Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) Viscoelastic
Rong ZENG Yi ZHANG Mei TU Changren ZHOU
Department of Materials Science and Engineering, College of Science and Engineering, Jinan Universit Department of Materials Science and Engineering, College of Science and Engineering, Jinan Universit
国际会议
重庆
英文
1219-1223
2008-06-09（万方平台首次上网日期，不代表论文的发表时间）