Study of Electrospun PLLACL Nanofibrous Mats for Drug Delivery System
In the present study an innovative tissue engineering scaffold was developed which can be used on wound dressing with a controllable drug-releasing capability. By coaxial electrospinning a coaxial nanofibrous mats were obtained which was made from Poly(L-lactid-co-ε-caprolactone) (PLLACL) and Tetracycline Hydrochloride (TCH), with P(LLA-CL) as the shell and TCH as the core. The TCH release behavior of the coaxial nanofibrous mats was measured by ultraviolet-visible (UV-vis) spectroscopy in vitro environment of 37℃ for a maximum 180 hours. To compare with the method of mix electrospinning, TCH without any other material could encapsulated in P(LLA-CL) nanofibers very well and released for a long time.
Electrospinning Nanofibers Drug Delivery System Antibacterial
Shuiping LIU Xiaoqiang LI Yan SU Lianjiang TAN Yu ZHANG Yanmo CHEN
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials,Donghua University, S State Key Laboratory for Modification of Chemical Fibers and Polymer Materials,Donghua University, S
国际会议
重庆
英文
1319-1322
2008-06-09（万方平台首次上网日期，不代表论文的发表时间）