Crosslinked Microparticle Preparation in Supercritical Carbon Diozide with Photopolymerization
An antisolvent processing technique by simultaneous compressed antisolvent precipitation and photopolymerization for cross-linked polymer microparticles formation was presented in this paper. In this process, photopolymerization of the homogeneous solution composed of methylene chloride, diphenyl-(2,4,6-trimethylbenzoyl)-phosphine oxide (TPO) and poly(ethylene glycol)600 diacrylate (PEG600DA) resulted to microparticle when it was sprayed into supercritical carbon dioxide (scCO2) and simultaneously exposed to initiating light. High miscibility of the solvent in scCO2 made methylene chloride quickly extracted from the dispersion phase, leaving very high concentrations of monomer (PEG600DA) dispersed in scCO2.The high monomer concentration combined with photoinitiated polymerization facilitates rapid reaction rates and ultimately lead to polymer precipitation. Particle size and morphology were adjustable by changing the processing conditions, such as temperature and pressure.
Zhun Meng Pengzong Liang Yong He Jun Nie
State Key Lab of Chemical Resource Engineering, College of Material Science and Engineering, Beijing State Key Lab of Chemical Resource Engineering, College of Material Science and Engineering, Beijin
国际会议
The 31st International Congress on Imaging Science(第31届国际影像科学大会 ICIS2010)
北京
英文
783-786
2010-05-12（万方平台首次上网日期，不代表论文的发表时间）