BONELIKE APATITE FORMATION ON PHOSPHATE BASED BIOACTIVE GLASSES IN SIMULATED BODY FLUID
The presence of bioactivity in glass was proved by Hench with the experimental studies of both in-vitro and in-vivo. Phosphate based glasses have many unique properties compared with silicate glasses, the most interesting of which, from a biomedical point of view, is its ability to dissolve completely in aqueous media. Further-more this dissolution behavior may be easily altered. New phosphate based bioactive glasses with 47P2O5-30.5CaO-(22.5-x) Na2O-(x) TiO2 (where x=0, 0.5, 1.0, 1.5) have been prepared by the conventional meltquenching technique. The amorphous nature of the glasses was analyzed using XRD study. The in-vitro responses of the prepared phosphate containing bioactive glasses were studied by immersing the fine polished specimens in simulated body fluid (SBF) for 15 days at 36.5℃ with Ph of 7.30.SBF has ionic concentration as equal to blood plasma. The SBF solution has been prepared by dissolving NaCl, NaHCO3, KCl, K2HPO4·3H2O, MgCl2·6H2O, and CaCl2 in distilled water. Surface morphological changes after in-vitro analysis of the glass samples were analyzed using SEM. Bone like apatite (Hydroxyapatite, HAP), formed on the surface of phosphate glasses after in-vitro test has been confirmed by FTIR. This kind of layer formation on the surface through in-vitro test proved the basic property of biocompatible status of phosphate glass samples with SBF.
A.MAHESWARAN G.HIRANKUMAR S.SELVASEKARAPANDIAN C.AMBIKA A.MARIKANI
Department of Physics, Kalasalingam University, Krishnankoil-626 190,Tamilnadu, India Department of physics, Mepco Schlenk Engineering College,Sivakasi - 626 005, India
国际会议
The 12th Asian Conference on Solid State Ionics(第十二届亚洲固态离子学会议暨第十五届中国固态离子学会议)
武汉
英文
1155-1160
2010-05-02（万方平台首次上网日期，不代表论文的发表时间）