Fabrication of a Glucose Biosensor by Co-immobilizing Palladium Nanoparticles and Glucose Ozidase onto Pd Electrode
Since Clark and Lyons proposed in 1962 the initial concept of glucose enzyme electrodes 1, impressive advances in the design and use of glucose biosensors has been achieved in our research group 2-5. Among those electrochemical biosensors, nanomaterials including carbon nanofiber 6, gold nanoparticles 7, 8 and semiconductor quantum dots 9-11 prove to be useful enzyme-immobilized platforms for fabricating highly sensitive glucose biosensors because of their potential use in diagnostic analysis of diabetes 12. In this presentation, we report a highly sensitive electrochemical glucose sensor based on an immobilized palladium nanoparticles-glucose oxidase (PdNPs-GOx) monolayer film deposited on a Pd elelctrode. The proposed biosensor possesses the advantages of fast response (<10 s) and low limit of detection (7.6 μM), and can be applied to determine glucose in various matrices such as blood, urine, and beverages.
Chuan DONG Zhongping LI Martin M. F. CHOI Shaomin SHUANG
Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan 030006, P.R. Ch Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, P.R .China
国际会议
The Twelfth International Symposium on Electroanalytical Chemistry(第十二届国际电分析化学会议 12th ISEC)
长春
英文
29-31
2009-08-12（万方平台首次上网日期，不代表论文的发表时间）