Ultrasensitive Detection of DNA Hybridization by Single Silver Nanoparticle Counting
Detection of specific DNA sequences is extremely important in the fields of gene analysis, clinical disease diagnosis, forensic applications, tissue matching research, bioterrorism prevention and a variety of other biochemical studies. A number of methods of DNA detection have been developed including optical, chemiluminescence, surface plasmon resonance Raman spectroscopy, hyper-Rayleigh Scattering (HRS), colorimetry and electrochemistry. In order to improve sensitivity and high-throughput, recently, great developments in laser-based detection of fluorescent molecules have made it possible. Such as fluorescence correlation spectroscopy (FCS), fluorescence cross correlation spectroscopy (FCCS), laser-induced fluorescence polarization (LIFP), single molecule fluorescence resonance energy transfer (smFRET), single-molecule two-color coincident detection assay, et al.
Fagong XU Jicun REN
College of Chemistry & Chemical Engineering, Shanghai Jiaotong University, 800 Dongchuan Road, Shanghai, 200240, P. R. China
国际会议
The Twelfth International Symposium on Electroanalytical Chemistry(第十二届国际电分析化学会议 12th ISEC)
长春
英文
58-59
2009-08-12（万方平台首次上网日期，不代表论文的发表时间）