A Sensitive Choline Biosensor with Supramolecular Architecture
The strategies for enzyme immobilization are critical in various enzyme biosensors. Nowadays, many enzyme biosensors have been developed based on the physical adsorption on the glassy carbon or carbon paste electrodes (mainly graphite). However, the reproducibilities of these biosensors are not so satisfactory. Covalent immobilization is readily to inactivate the biomolecules on the electrode surface. More recently, supramolecular association has attracted considerable attention, since the biomolecular activity can be effectively retained 1. The most common host molecules are various cyclodextrins, which are a class of cyclic oligosaccharides with a hydrophobic inner cavity and a hydrophilic outside surface, and can form stable inclusion complexes with organic molecules through hydrophobic interaction. Lately, Villalongas group has developed a xanthine biosensor with supramolecular architecture 2. But to date there has been no report about the choline biosensor via supramolecular associations.
Zhanxia ZHANG Xiurong YANG
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chine Graduate School of the Chinese Academy of Sciences, Beijing 100039, China
国际会议
The Twelfth International Symposium on Electroanalytical Chemistry(第十二届国际电分析化学会议 12th ISEC)
长春
英文
269-271
2009-08-12（万方平台首次上网日期，不代表论文的发表时间）