Effect of biphasic calcium phosphate nanocomposite on healing of surgically created alveolar bone defects in beagle dogs
The aim of the present study was to investigate the effect of porous biphasic calcium phosphate nanocomposite (nanoBCP) scaffolds bioceramic. Alveolar bone defects were surgically created bilaterally at the buccal aspects of the upper second premolar in fourteen beagle dogs. After root conditioning with ethylenediaminetetraacetate (EDTA), nanoBCP was randomly filled in the defects and nothing was put into the contralaterals as controls. Dogs were killed at the 12th weeks. Histological observations were processed through a light microscopy. The results revealed that a great amount of functional periodontal fissures formed in the defects in the nanoBCP groups while minimal bone took shape in the controls. In this study, nanoBCP has proved to work well as a biocompatible and osteoconductive scaffold material to promote periodontal regeneration effectively.
Lanlei Wang Aizhong Guan Han Shi Yangxi Chen Yunmao Liao
State Key Laboratory of Oral Diseases,Sichuan University,Chengdu,Sichuan Province,610041,China Linyi Peoples Hospital,Linyi,Shandong,276000,China
国际会议
The 8th China International Nanoscience and Technology Symposium(2009第八届中国国际纳米科技湘潭研讨会Cinsts09)
湖南湘潭
英文
1-5
2009-10-23（万方平台首次上网日期，不代表论文的发表时间）