Preclinical Optical Molecular Imaging of cancer with tumor-selective molecular probes

摘要：

Introduction Accurate and rapid detection of tumors is of great importance for interrogating the molecular basis of cancer pathogenesis, preventing the onset of complications, and implementing a tailored therapeutic regimen. In this era of molecular medicine, molecular probes that respond to, or target molecular processes are indispensable. While many human diseases have been studied successfully by using intrinsic optical properties of normal and pathologic tissues, molecular imaging of the expression of aberrant genes, proteins, and other pathophysiologic processes would be enhanced by the use of highly specific exogenous molecular probes. As progress in molecular medicine continues to reveal specific factors that characterize abnormal tissues, a combination of advances in instrumentation and new optical molecular probes are needed to fully realize the potential of molecular imaging of human diseases.

作者: Samuel Achilefu

作者单位: Washington University School of Medicine, Department of Radiology, 4525 Scott Avenue, St. Louis, MO 63110

会议类型: 国际会议

会议名称: Yangtze River 2009 International Conference on Medical Imaging Physics & The 5th National Annual Meeting of Medical Imaging Physics(长江2009国际医学影像物理和工程大会暨第五届中国医学影像物理学术年会ICMIP2009)

会议地点: 南京

会议语种:英文

页码: 4-5

在线出版日期: 2009-10-23（万方平台首次上网日期，不代表论文的发表时间）