The Effect of Positive-indefinite Matriz on the Magnetic Resonance Diffusion Tensor-derived Parameters

To evaluate the effect of the positive-indefinite matrix on the diffusion tensor-derived parameters, and to propose a modified algorithm for calculating these parameters. Magnetic resonance diffusion tensor images of five healthy volunteers were obtained. The diffusion sensitive gradient magnetic fields were applied along 25 directions and the diffusion weighting value was 1000 s/mm2. Many positive-indefinite diffusion tensors could be found in the area of white matter, such as the genu and splenium of corpus callosum. Due to the positive-indefinite matrix, the mean diffusivity and fractional anisotropy were underestimated and overestimated respectively using conventional algorithm. We modified the conventional algorithm by using absolute value of all eigenvalues. The results showed that the robustness and reliability for deriving these parameters could be improved by our algorithm.
diffusion tensor imaging functional magnetic resonance imaging DTI MRI
ZHANG Huai-Li REN Hong-Run HE Qing GAO Song
Medical Physics Department, Guangdong Medical College, Dongguan, Guangdong .P.R.China Basic Medical Sciences Department, Beijing Medical School, Beijing, P.R.China Beijing Key Lab of Medical Physics and Engineering, Peking University, Beijing 100191, P.R.China
国际会议
南京
英文
95-99
2009-10-23(万方平台首次上网日期,不代表论文的发表时间)