Systematic Study on Imaging Characteristics of Rat Model of Parkinsons Disease

摘要：

Imaging technology was utilized for systematic study on brain morphology and function of model rat of Parkinson’s disease (PD): magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) were used to get morphological imaging data; functional imaging data such as spectroscopy and blood flow changes were obtained by proton magnetic resonance spectroscopy (1H-MRS) and CT perfusion (CTP). The results show that PD model rats have no characteristic morphological imaging abnormalities, but regional cerebral blood flow (CBF) reduction and spectral changes in striatum.

关键词： parkinsons disease imageology magnetic resonance imaging CT perfusion

作者: HU Guang-Xia QIAN Zhi-Yu SUN Tao YANG Tian-Ming WANG Wen-Hong

作者单位: Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 21 Department of Neurosurgery, Zhongda Hospital, Southeast University, Nanjing 210009, China

会议类型: 国际会议

会议名称: Yangtze River 2009 International Conference on Medical Imaging Physics & The 5th National Annual Meeting of Medical Imaging Physics(长江2009国际医学影像物理和工程大会暨第五届中国医学影像物理学术年会ICMIP2009)

会议地点: 南京

会议语种:英文

页码: 188-193

在线出版日期: 2009-10-23（万方平台首次上网日期，不代表论文的发表时间）