Preparation and Characterization of Water-Soluble Near-infrared Emitting PbS Quantum Dots
In this paper, we report a new facile method to prepare water-soluble near-infrared (NIR)-emitting PbS quantum dots (QDs), using N-acetyl-L-cysteine (NAC, a derivate of L-cysteine) as its stabilizer. We explored intensively the influence of the precursor Pb/S molar ratio, the Pb/NAC molar ratio, and the pH of original solution on optical properties. The results showed that aqueous PbS QDs with strong NIR fluorescence could be prepared, and their photoluminescence emission peaks could be tuned from ~895 nm to 970 nm. The preliminary studies have indicated that such aqueous quantum dots have a potential application in biomedical imaging, especially in noninvasive in vivo fluorescence imaging. In addition, the resulting PbS quantum dots were further characterized by transmission electron microscopy and X-ray diffraction analysis.
pbs quantum dots N-acetyl-L-cysteine near-infrared biomedical imaging
CAO Jie LI Shan DENG Da-Wei Gu Yue-Qing
Department of Biomedical Engineering, School of Life Science and Technology, China Pharmaceutical Un Department of Biomedical Engineering, School of Life Science and Technology, China Pharmaceutical Un
国际会议
南京
英文
327-334
2009-10-23（万方平台首次上网日期，不代表论文的发表时间）