Effects of Deozynivalenol,Nivalenol,T-2 Tozin and Selenium on the Metabolism of Tissue EngineeredCartilage In Vitro
(0) Kashin-Beck Disease (KBD) is an endemic,chronic,degenerative osteoarthropathy,which is manifest primarily in agricultural regions in Asia especially in the central regions of China.KBD often occurs in children and is age-related. The symptoms include joint pain,morning stiffness in the joints,disturbances of flexion and extension in the elbows,enlarged inter-phalangeal joints and limited motion in the middle-sized and large joints of the body.Pathologically,the epiphyseal plate of cartilage from young and adolescent patients shows necrosis in the hypertrophic layer near the adjacent subchondral bone thus explaining why these young KBD patients often have severe joints deformities during development.
Junling Cao Jianhong Zhu Clare E.Hughes Bruce Caterson Minling Lu Fuqiang Liu Qiang Fu Jiayuan Liu Siyuan Li Jinghong Chen An Zhang Zengtie Zhang
Institute of Endemic Diseases,College of Medicine,Xian Jiaotong University Key Laboratory of Enviro Laboratory of Connective Tissue Biology,School of Biosciences,Cardiff University,Cardiff,CF10 3US,UK
国际会议
The First International Conference on Selenium in the Environment and Human Health(第一届硒与环境和人体健康国际会议)
苏州
英文
53-54
2009-10-01（万方平台首次上网日期，不代表论文的发表时间）