Synthesis of Unsymmetric Ureas by Selenium-Catalyzed Redoz Carbonylation Reactions of Nitroarenes and Amines

摘要：

Unsymmetric ureas,which contain peptide bond (CONH-),are usually bioactive and widely used as herbicides,agrochemicals,and Pharmaceuticals.However,industrial production processes of the chemicals involve highly toxic and corrosive phosgene.Catalytic carbonylation reactions with carbon monoxide (CO) are extensively investigated nowadays and seem to be promising alternative substitute for the phosgene technology.Generally,noble metals (such as rhodium,ruthenium,and palladium) are utilized as the catalysts.However,elemental selenium (Se) was reported to catalyze the carbonylation reaction of nitro-or amino compounds in recent years.Herein we present our research results on the use of redox carbonylation of nitroarenes and amines to synthesize unsymmetric ureas in one pot.

作者: Y.Yang J.T.Mei J.Z.Chen G.Ling X.H.Yuan S.W.Lu

作者单位: National Engineering Research Center for Catalysis,Dalian Institute of Chemical Physics,Chinese Academy of Sciences,457 Zhongshan Road,Dalian,Liaoning 116011,China

会议类型: 国际会议

会议名称: The First International Conference on Selenium in the Environment and Human Health(第一届硒与环境和人体健康国际会议)

会议地点: 苏州

会议语种:英文

页码: 105-106

在线出版日期: 2009-10-01（万方平台首次上网日期，不代表论文的发表时间）