Selective Formation of Unsymmetric Ureas by Selenium Catalyzed Redoz Carbonylation of CO

摘要：

Symmetric,unsymmetric,substituted ureas that contain the peptide bond (-CONH-) and possess biological activities,are widely used as herbicides,agrochemicals and pharmaceuticals. The methods for their industrial synthesis use phosgene as one of the reagents,although phosgene is highly toxic and produces a lot of corrosive contaminants.In recent years,attention has been paid to a very promising non-phosgenic process for the synthesis of various unsymmetric ureas,namely,the reductive carbonyla tion of nitro-compounds or the oxidative carbonylation of anilines catalyzed by noble metals,including rhodium,ruthenium and palladium.However,oxidative carbonylation of amines or reductive carbonylation of nitro-compounds by selenium (Se) catalysts instead of noble metals has recently been reported to also give symmetric ureas.

作者: J.T.Mei Y.D.Luo Y.Xue S.W.Lu

作者单位: Dalian Naval Institute,667 Jiefang Road,Dalian 116018,China Dalian Institute of Chemical Physics,Chi Dalian Naval Institute,667 Jiefang Road,Dalian 116018,China Dalian Institute of Chemical Physics,Chinese Academy of Sciences,161 Zhongshan Road,Dalian 116012,Ch

会议类型: 国际会议

会议名称: The First International Conference on Selenium in the Environment and Human Health(第一届硒与环境和人体健康国际会议)

会议地点: 苏州

会议语种:英文

页码: 113-114

在线出版日期: 2009-10-01（万方平台首次上网日期，不代表论文的发表时间）