Randomized Controlled Trials of the Efficacy of Lung Cancer Screening by Sputum Cytology Revisited

摘要：

BACKGROUND:Two randomized controlled trials of lung cancer screening initiated-in the 1970s,the Johns Hopkins Lung Project and the Memorial Sloan-Kettering Lung Study,compared 1 arm that received annual chest X-ray and 4-monthly sputum cytology (dual-screen) to a second arm that received annual chest X-ray only.Previous publications from these trials reported similar lung cancer mortality between the 2 groups.However,these findings were based on incomplete follow-up,and each trial on its own was under-powered to detect a modest mortality benefit.

关键词： Iung cancer screening sputum cytology chest X-ray

作者: V.Paul Doria-Rose Pamela M.Marcus Eva Szabo Melvyn S.Tockman Myron R.Melamed Philip C.Prorok

作者单位: Blometry Research Group,Division of Cancer Prevention,National Cancer Institute,National Institutes Blometry Research Group,Division of Cancer Prevention,National Cancer Institute,National Institutes Lung and upper Aerodigestive Cancer Research Group,Division of Cancer Prevention,National Cancer Ins Rish Assessment,Detection,and Intervention Program,Department of Cancer Prevention and Control,H.Lee Department of Pathology,New York Medical College,Valhalla,New York

会议类型: 国际会议

会议名称: 21st International Conference on Screening for Lung Cancer(第21届国际肺癌筛查大会)

会议地点: 珠海

会议语种:英文

页码: 125-135

在线出版日期: 2009-10-01（万方平台首次上网日期，不代表论文的发表时间）