Steady-state Optimization Model and Algorithm of Glycerol Bioconversion to 1,3-Propanediol in Continuous ulture

摘要：

This paper focuses on the improvement of the concentration and productivity of 1,3propanediol from continuous fermentation of glycerol by Klebsieila pneumoniae. A nonlinear steady-state optimization model is presented according to engineering background. A new linear approximating method has been developed in view of the feature of the optimization model. Computer simulation is used for this paper, and the numerical simulation is in accordance with experimental results. The numerical results illustrate the validity and efficiency of the algorithm. The results presented in this work can be used as guidelines for choosing proper operating parameters to get higher concentration or productivity.

关键词： Steady-state Optimization Nonlinear Kinetic System Nonlinear Programming Linear Approzimation Algorithm

作者: An Li En-Min Feng Pei-Jun Guo Jian-Xiong Ye

作者单位: School of Mathematical Sciences,Xiamen University,Xiamen 361005,China School of athematical Sciences,Dalian University of Technology,Dalian 116023,China Department of anagement System Science,Faculty of Business Administration,Yokohama National Universi School of Mathematical Sciences,Dalian University of echnology,Dalian 116023,China

会议类型: 国际会议

会议名称: The 3rd International Symposium on Optimization and System Biology(第三届最优化与系统生物学国际会议 OSB09)

会议地点: 张家界

会议语种:英文

页码: 177-183

在线出版日期: 2009-09-20（万方平台首次上网日期，不代表论文的发表时间）