Nanorod Arrays Containing Nanocrystalline Pharmaceuticals by Bondestructive Eztraction from Porous Templates: A Material Platform for Biomedical Applications

摘要：

Uncontrolled crystallization and aging of polymorphic pharmaceuticals during production and storage is a severe drawback for their controlled release under physiological conditions. Therefore, it would be highly desirable to design biodegradable drug delivery systems in which the crystallinity of the pharmaceuticals, the formation of specific crystal modifications and even crystalline textures could be controlled, or in which even the amorphous state could be stabilized. A promising but still-challenging strategy to realize such systems is the encapsulation of pharmaceuticals in nanocontainers, which would, moreover, allow the transport and enrichment of the pharmaceuticals to specific sites in the human body.

作者: Mario Beiner Martin Steinhart Silko Grimm T. R. Gopalakrishnan Jaime Martin Perez Gema Rodriguez Mar Fernandez Ulrich Gosele Julio San Roman Carmen Mijangos

作者单位: Institute of Physics, Martin Luther University Halle-Wittenberg, Germany Max Planck Institute of Microstructure Physics, Germany Institute for Chemistry, University of Osna Max Planck Institute of Microstructure Physics, Germany Institute for Chemistry, University of Osnab Institute of Physics, Martin Luther University Halle-Wittenberg, Germany Institute for Chemistry, U Instituto de Ciencia y Tecnologia de Polimeros, CIBER-BBN, CSIC, Madrid, Spain Institute for Chemistry, University of Osnabrück, Germany

会议类型: 国际会议

会议名称: International Symposium on Crystal Engineering and Drug Delivery System 2009(2009晶体工程与药物传送系统国际会议)

会议地点: 天津

会议语种:英文

页码: 20-21

在线出版日期: 2009-09-05（万方平台首次上网日期，不代表论文的发表时间）