CFD Study on Continuous Crystallization Process with Multiphase Population Model
Continuous crystallization was commonly used for crystallization process. Even the process was studied for many years, the operation and process design was still difficult to fit the requirement of the product. The reason is that the model used in process design was based on the mixed suspension 1. However, the industrial crystallizers were difficult to be operated as the model requirement because the mixed crystal suspension was difficult to be fullfitted 2. It has been experimentally proved that different sizes of particle have different suspension distributions in the crystallizer. The suspension density distribution in the crystallizer affect strongly on the crystal growth and nucleation process, even on the product size distribution. On the other hand, other parameters which affect crystallization process such as supersaturation have also distribution in the crystallizer. The effect of all parameter distributions has to be compactly considered in the continuous crystallization process design so that the product crystal size distribution can be accurately estimated. However, those distributions are difficult and very cost to be obtained by experimental method. The aim of this study is to simulate the effect of the operation condition on the crystal size distribution in the product by using CFD multiphase population model 3. The commercial software ANSYS CFD was employed. The crystallization process was simulated by considering the suspension density distributions with different sizes of particle. The flow hydrodynamics, the suspension density distributions of different sizes of particle, the supersaturation distributions and particle size distribution were obtained.
SHA Zuoliang WU Shouxiang
Tianjin Key Laboratory of Marine Resource & Chemistry，Tianjin University of Science & Technology，Tianjin 300457，China
国际会议
International Symposium on Crystal Engineering and Drug Delivery System 2009(2009晶体工程与药物传送系统国际会议)
天津
英文
60-62
2009-09-05（万方平台首次上网日期，不代表论文的发表时间）