Crystal Growth and Polymorphic Transformation -A Case Study: Carbamazepine Crystallization

摘要：

Polymorphism, in which multiple crystal forms exist for the same chemical compound, is of significant interest to the pharmaceutical industry. It has been found for nearly 200 years. The variation in physical properties, such as crystal shape, solubility, hardness, color, melting point, and chemical reactivity makes polymorphism an important issue for the food, specialty chemical and pharmaceutical industries, where products are specified not by only chemical composition, but also by their performance. Control over desired performance properties requires therefore control over the formation of the desired polymorphic structure. Many parameters influence the formation of polymorphs: temperature, pressure, supersaturation, solvent, seeding and additives.

会议类型: 国际会议

会议名称: International Symposium on Crystal Engineering and Drug Delivery System 2009(2009晶体工程与药物传送系统国际会议)

会议地点: 天津

会议语种:英文

页码: 70

在线出版日期: 2009-09-05（万方平台首次上网日期，不代表论文的发表时间）