Particle Size Control of Hydrochlorothiazide by Supercritical Fluid Crystalline Technology

摘要：

Particle size reduction was the efficient method to improve the water-solubility and bioavailability for insoluble drug. The supercritical fluid technology has been applied in particle preparation for its high diffusivity, high compression, low viscosity and easy control.

关键词： supercritical fluid particle size control hydrochlorothiazide

作者: Liu Jun-wei Yin Lei Sun Yong-da

作者单位: Tianjin Crystec Pharmaceutical Technology Limited, Tianjin 300457, China

会议类型: 国际会议

会议名称: International Symposium on Crystal Engineering and Drug Delivery System 2009(2009晶体工程与药物传送系统国际会议)

会议地点: 天津

会议语种:英文

页码: 154

在线出版日期: 2009-09-05（万方平台首次上网日期，不代表论文的发表时间）