Determination and Correlation of Valsartan Solubility in Ethyl Acetate/N-Hezane Binary Miztures

摘要：

The solubility of valsartan in ethyl acetate/n-hexane binary mixtures was measured by a synthetic method over the temperature range from 278.15 K to 313.15 K at atmosphere pressure. The results show that the solubility of valsartan increases with increasing temperature and decreases with the increasing mole fraction of n-hexane in the binary mixtures. The experimental data were correlated using the CNIBS/Redlich-Kister model and the agreement with the experimental data was very good.

作者: Liu Yan Gao Li Wang Jingkang

作者单位: School of Chemical Engineering and Technology, Tianjin University，Tianjin 300072 School of Chemical Engineering and Technology, Tianjin University， Tianjin 300072

会议类型: 国际会议

会议名称: International Symposium on Crystal Engineering and Drug Delivery System 2009(2009晶体工程与药物传送系统国际会议)

会议地点: 天津

会议语种:英文

页码: 159-165

在线出版日期: 2009-09-05（万方平台首次上网日期，不代表论文的发表时间）