Measurement and Correlation of the Solubility of γ-Aminobutyric Acid

摘要：

γ-aminobutyric acid (GABA) is a non-protein amino acid that is widely occurred in nature ， and has very important physiological functions. In this article, the solubility of γ-aminobutyric acid in aqueous ethanol solution was measured by a synthetic method at temperatures ranging from 288.2 K to 313.2 K and at atmosphere pressure. For the temperature range investigated, the solubilities of γ-aminobutyric acid in the solvents increased with increasing temperature. The solubility data were correlated with Apelblat equation and λh equation. The Apelblat equation can regress the solubility datamuch better than λh equation.

关键词： γ-aminobutyric acid Mized solvent Solubility

作者: Yang Wenge Lei Ziyu Chen Xiao Fu Shan Hu Yonghong

作者单位: College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology,Nanjing 210 College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 21

会议类型: 国际会议

会议名称: International Symposium on Crystal Engineering and Drug Delivery System 2009(2009晶体工程与药物传送系统国际会议)

会议地点: 天津

会议语种:英文

页码: 255-261

在线出版日期: 2009-09-05（万方平台首次上网日期，不代表论文的发表时间）